Podocalyxin-Like (PODXL) Peptid
PODXL
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981929
Kurzübersicht für Podocalyxin-Like (PODXL) Peptid (ABIN981929)
Target
PODXL
(Podocalyxin-Like (PODXL))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PODXL antibody (Catalog #: ARP44729_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Podocalyxin-Like (PODXL) peptide
PODXL Reaktivität: Human, Ratte, Maus, Hund Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PODXL (Podocalyxin-Like (PODXL))
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Hintergrund
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PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of PODXL include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Alias Symbols: Gp200, MGC138240, PCLP, PC, PCLP-1
Protein Interaction Partner: SELL,SLC9A3R2,SELL,SLC9A3R2
Protein Size: 526 -
Molekulargewicht
- 53 kDa
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Gen-ID
- 5420
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NCBI Accession
- NM_005397, NP_005388
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UniProt
- Q53ER6
Target
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